Adrenomedullin (AM) (13-52), human ( —— )

产品货号. M30555 CAS No. 154765-05-6

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HNMR

HPLC

MSDS

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产品名称

Adrenomedullin (AM) (13-52), human
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Adrenomedullin (13-52) is a 40 amino acid peptide with one intramolecular disulfide bridge, Adrenomedullin (13-52) is a high affinity ligand for the adrenomedullin receptor.
产品描述

Adrenomedullin (13-52) is a 40 amino acid peptide with one intramolecular disulfide bridge, Adrenomedullin (13-52) is a high affinity ligand for the adrenomedullin receptor.(In Vitro):The effects of Adrenomedullin (AM) (13-52), human [hADM-(13-52)] are investigated in the rat pulmonary vascular bed and in isolated rings from the rat pulmonary artery (PA). Under conditions of controlled blood flow and constant left atrial pressure when tone is increased with U-46619, injection of hADM-(13-52) produces dose-related decreases in lobar arterial pressure. hADM-(13-52) modulates receptor-mediated, but not voltage-dependent, pulmonary vascular contraction by influencing Ca2+ influx.
同义词

——
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靶点

Other Targets
受体

——
研究领域

——
适应症

——

CAS Number

154765-05-6
分子量

4533.1
分子式

C200H308N58O59S2
纯度

>98% (HPLC)
溶解度

——
SMILES

——
化学全称

Sequence:Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bridge: Cys16-Cys21)

Gumusel B, et al. Analysis of responses to adrenomedullin-(13-52) in the pulmonary vascular bed of rats. Am J Physiol. 1998 Apr;274(4 Pt 2):H1255-63.

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